15L-150L Secondary Stainless Steel Bioreactor System
15L-150L Secondary Stainless Steel Bioreactor System

15L-150L Secondary Stainless Steel Bioreactor System

Secondary stainless steel fermenter system suitable for process development and small-scale production, optional between 5L, 10L, 30L, 50L, 100L, 200L, 300L, 500L and 1000L
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Nominal volume: 5L-50L; 10L-100L; 15L-150L; 20L-200L; 30L-300L, 50L-500L; 100L-1000L

Diameter-height ratio: 1:2.5; Filling coefficient: 70%

10 liter 100 liter tank: the main material is all stainless steel 316L tank, there is no dead angle in the tank; with special sampling and discharging valve for fermentation tank, and transplanting pipeline. Using large viewing angle tank liquid level observation mirror, 12V safety sight light, with temperature, PH, DO, defoaming, liquid level interface, inoculation port, feeding port, and multiple spare ports, all welds are firm, neat and beautiful .

Tank body: Design pressure 0.3Mpa Jacket: Design pressure 0.3Mpa, the optimized diversion design is adopted to improve the exchange efficiency and the uniformity of the temperature in the tank;

Tank function: John Crane mechanical seal, air inlet sterilization filter, exhaust condenser, air inlet system with air distributor, flame inoculation port (also feeding port and cleaning port), discharge port, sampling port, Feeding port; five electrodes for automatic parameter control are: PH electrode, DO electrode, defoaming electrode, temperature electrode port; four peristaltic pumps are automatically controlled to supplement acid/alkali/foam/culture agent respectively;

Motor: Special motor for fermentation tank to ensure that the motor can run in harsh environments;

Ventilation: One-way deep ventilation is adopted, the flow rate of the gas is adjusted according to the process requirements, and the gas is distributed evenly by the air distributor in the tank; The material backflow device ensures safety and greatly prolongs the service life;

Stirring system: mechanical stirring system, John Crane mechanical seal, Fuji inverter;

Stirring form: straight-blade stirring paddle (second level) inclined blade stirring paddle (first-level), mechanical compression defoaming paddle (first-level), four baffle plates;

Fermentation pH control function: intelligent PID control, special Swiss Mettler PH electrode;

Fermentation dissolved oxygen control function: adopt intelligent PID control, special Swiss METTLER DO electrode;

Temperature control: electric heating, water cooling, circulating temperature control by circulating pump, with air self-escape function and water cut-off and over-temperature protection functions, with good heat exchange efficiency; intelligent module control not only ensures the rapidity of temperature control but also achieves energy saving ;

Feeding: The perfect feeding system (acid, alkali, foaming enemy, culture medium) can be used for quantitative feeding at regular intervals; the four peristaltic pumps can be separately set in sections on the control interface, which is convenient and flexible in actual use. Equipped with specially designed feeding pins to ensure the safe operation of feeding;

Automatic tank cover lifting system (optional): BLBIO-UIP300 automatic tank cover lifting system lifts the tank cover through an electric system to facilitate cleaning and maintenance of the equipment in the tank;

LBR-A type, B type, C type, D type, S type control system optional: German Siemens S7-200 series PLC control system + 10" LCD touch screen display operation, on-site direct operation (menu type), full Chinese menu and Interface; sample and display tank data, browse and analyze system data, read settings. Can control the stirring speed, the temperature of the medium in the tank, the Ph value, and the DO value;


1. It can set the upper and lower limits of temperature, speed, Ph value, DO value, and has the function of over-limit alarm;

2. With super liquid level alarm and automatic replenishment function, with super foam level alarm and automatic addition of defoamer function;

3. All alarm accidents can be recorded and consulted;

4. Speed, temperature, Ph value, DO value, etc. can be set to automatic or off;

5. The parameters of the medium temperature, stirring speed, Ph, DO and other parameters in the tank can be controlled by setting the curve according to the process requirements;

6. Each parameter has PID adjustment process display, such as set value, real-time value, PID set value, upper and lower limit value, curve display, manual/automatic switching, online setting, etc.;

7. The historical data and curves of various parameters can be saved for many years, and the real-time curve can be restored as it is when the power is turned off and restarted;

8. Friendly man-machine interface, can switch more than a dozen monitoring screens;

9. It has the function of feeding and measuring; regular quantitative feeding;

10. The system has a variety of related controls: the related control of speed and dissolved oxygen, the related control of feeding and dissolved oxygen, the related control of feeding and pH value, etc.;

11. The system has real-time display, data recording and data analysis of the running process

12. The parameters of each detection and control loop can be manually set and corrected online on the screen, and the temperature, DO, PH sensors can be adjusted and adjusted, and the flow rate of each peristaltic pump can be calibrated; the operation has a password protection function, and the password is divided into operation. Member and administrator level passwords;

13. Automatically record the start-up time, shutdown time of the fermentation tank, the number of power outages during automatic operation, the outage time, the call time, etc.;

14. The software system has the ability of self-adaptation and self-diagnosis;


bioreactor fermenter project case